"Most of the psychiatric drugs we use today are refinements of drugs whose value for mental disorders was discovered by accident decades ago. Now we can look forward to a more rational way to design psychiatric drugs. It will be guided by the identification of the gene variants that predispose certain people to particular mental disorders such as schizophrenia or severe depression."
"An autonomous agent is something that can both reproduce itself and do at least one thermodynamic work cycle. It turns out that this is true of all free-living cells, excepting weird special cases. They all do work cycles, just like the bacterium spinning its flagellum as it swims up the glucose gradient. The cells in your body are busy doing work cycles all the time."
"We've already had a digital revolution; we don't need to keep having it. The next big thing in computers will be literally outside the box, as we bring the programmability of the digital world to the rest of the world. With the benefit of hindsight, there's a tremendous historical parallel between the transition from mainframes to PCs and now from machine tools to personal fabrication. By personal fabrication I mean not just making mechanical structures, but fully functioning systems including sensing, logic, actuation, and displays."
"The kind of Christianity that pervades the religious right in this country divides the world between the saved and the damned, between God's people and Satan's people, between good and evil. We have all seen how this is played out in our politics. I used to think that President Bush was using this language as a political ploy. I still think he is, but I also think—to my disappointment—that he also believes it. His conviction that he is God's chosen one to "rid the world of evildoers" blinds him to the evil that he—and we, as Americans—are capable of doing. The conviction that we are on the side of good—of God—is, however, an ancient one—enormously powerful."
something about his life and his attitude toward the world and toward physics.
"I'm interested in bending the edges of the spectrum to make the abstract and the concrete hit one another more directly."
"The substance of what I'm interested in is that it's the genes that are related to behavior, and how they work. The big insight is that genes are the agents of nurture as well as nature. Experience is a huge part of a developing human brain, the human mind, and a human organism. We need to develop in a social world and get things in from the outside. It's enormously important to the development of human nature. You can't describe human nature without it. But that process is itself genetic, in the sense that there are genes in there designed to get the experience out of the world and into the organism. In the human case you're going to have genes that set up systems for learning that are not going to be present in other animals, language being the classic example. Language is something that in every sense is a genetic instinct. There's no question that human beings, unless they're unlucky and have a genetic mutation, inherit a capacity for learning language. That capacity is simply not inherited in anything like the same degree by a chimpanzee or a dolphin or any other creature. But you don't inherit the language; you inherit the capacity for learning the language from the environment."
"For the humans who would like to know what it takes to be an alpha man—if I were 25 and asked that question I would certainly say competitive prowess is important—balls, translated into the more abstractly demanding social realm of humans. What's clear to me now at 45 is, screw the alpha male stuff. Go for an alternative strategy. Go for the social affiliation, build relationships with females, don't waste your time trying to figure out how to be the most adept socially cagy male-male competitor. Amazingly enough that's not what pays off in that system. Go for the affiliative stuff and bypass the male crap. I could not have said that when I was 25."
"We're beginning to get some revolutionary new ideas about how social behavior originated, and also how to construct a superorganism. If we can define a set of assembly rules for superorganisms then we have a model system for how to construct an organism. How do you put an ant colony together? You start with a queen ant, which digs a hole in the ground, starts laying eggs, and goes through a series of operations that raise the first brood. The first brood then goes through a series of operations to breed more workers, and before long you've got soldier ants, worker ants, and foragers, and you've got a teeming colony. That's because they follow a series of genetically prescribed rules of interaction, behavior, and physical development. If we can fully understand how a superorganism is put together, we'll come much closer to general principles of how an organism is put together. There are two different levels—the cells put together to make an organism, organisms put together to make a superorganism. Right now I'm examining what we know to see if there are rules of how superorganisms are put together."