Time Does Not Exist
Contrary to what generally assumed, the physical world does not exist "in time". At the basic microscopic level, the world is better described in terms of a a-temporal theory, where physical laws do not express time evolution of physical variables, but just relations between variables. Time emerges only thermodynamically when describing macroscopic variables. Therefore time is only a side effect of our ignorance of the microscopic state of the world. "Time is a side effect of ignorance."
Space Does Not Exist
The physical world does not exist "in space". The physical world is made by an ensemble of particles and fields, which do not live in an external space, but rather live "on each other", and which can be in a relation of contiguity with respect to one another. "Space" is the order implied by this relation. These two principles are implied by what we have learned about the physical world with general relativity and with quantum mechanics. The second principle is largely a return to the Pre-Newtonian relational understanding of space, while the first has few antecendents in our culture.