To arrive at the edge of the world's knowledge, seek out the most complex and sophisticated minds,
put them in a room together, and have them ask each other the questions they are asking themselves.
Links:
[1] http://edge.org/news/the-scientist-two-responses-to-edgeorg%E2%80%99s-the-world-question-center-2011
[2] http://tinyurl.com/bcsqxfy
[3] http://www.the-scientist.com/article/display/58125/