To arrive at the edge of the world's knowledge, seek out the most complex and sophisticated minds,
put them in a room together, and have them ask each other the questions they are asking themselves.
Links:
[1] http://edge.org/news/streetdogs-things-long-held-true-that-turned-out-false-to-our-consternation
[2] http://www.businessday.co.za/articles/Content.aspx?id=135583