To arrive at the edge of the world's knowledge, seek out the most complex and sophisticated minds,
put them in a room together, and have them ask each other the questions they are asking themselves.
Links:
[1] http://edge.org/news/jennifer-jacquet-brian-eno-the-young-economist-and-the-musical-polymath-discuss-shame
[2] http://is.gd/ZIibBI
[3] http://www.edge.org/documents/press/AnOther.pdf
[4] http://edge.org/memberbio/jennifer_jacquet